Study 1: Body Weight Gain, Parkinson, Subthalamic Stimulation
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Parkinson's Disease
Interventions:
Behavioral: Energy metabolism by chronic bilateral subthalamic stimulation
Sponsor/Collaborators: University Hospital, Clermont-Ferrand
Gender: Both
Age Groups: Adult|Senior
Phases: Phase 2
Enrollment: 32
Funded Bys: Other
Study Types: Interventional
Study Designs: Allocation: Non-Randomized|Intervention Model: Single Group Assignment|Primary Purpose: Prevention|Masking: Open Label
Other IDs: CHU-0024
First Received: September 13, 2007
Start Date: September 2007
Completion Date: June 2009
Last Updated: January 18, 2011
Last Verified: January 2011
Acronym: null
Results First Received: No Study Results Posted
Primary Completion Date: May 2009
Outcome Measures: heart rate recorded during 7 days in usual conditions of life|energy expenditure recorded during 14 days in usual conditions of life with normalized water (18O 10 %) and Deuterium oxide (99.94 %D)
URL: http://ClinicalTrials.gov/show/NCT00529724
Study 2: Electronic-health Application To Measure Outcomes REmotely Clinical Trial
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Neurodegenerative Disease|Weight Loss|Amyotrophic Lateral Sclerosis|Parkinson's Disease|Huntington's Disease|Cachexia
Interventions: Behavioral: In-Person Nutritional Counseling by a Registered Dietitian|Behavioral: Nutritional counseling using an e-Health Application
Sponsor/Collaborators: Massachusetts General Hospital|ALS Association
Gender: Both
Age Groups: Adult|Senior
Phases: Phase 2
Enrollment: 150
Funded Bys: Other
Study Types: Interventional
Study Design: Allocation: Randomized|Endpoint Classification: Bio-equivalence Study|Intervention Model: Parallel Assignment|Primary Purpose: Supportive Care|Masking: Open Label
Other IDs: 2015P000258
First Received: April 6, 2015
Start Date: April 2015
Completion Date: June 2017
Last Updated: April 13, 2015
Last Verified: April 2015
Acronym: EAT MORE
Results First Received: No Study Results Posted
Primary Completion Date: December 2016
Outcome Measures: Weight: Measured in the clinic|Calorie intake: Measured using 4 day food records|Safety: Frequency of adverse events|Tolerability: The number of participants who complete the study while complying with at least 80% of the counseling sessions
URL: http://ClinicalTrials.gov/show/NCT02418546
Study 3: Weight Loss in Parkinson's Disease and Role of Small Bowel Bacterial Overgrowth
Recruitment: Completed
Study Results: No Results Available
Conditions: Parkinson's Disease
Interventions: Drug: Rifaximin
Sponsor/Collaborators: Mayo Clinic
Gender: Both
Age Groups: Adult|Senior
Phases: Phase 3
Enrollment: 49
Funded Bys: Other
Study Types: Interventional
Study Designs: Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label
Other IDs: 11-006817
First Received: August 7, 2012
Start Date: September 2012
Completion Date: March 2015
Last Updated: May 20, 2015
Last Verified: May 2015
Acronym: null
Results First Received: No Study Results Posted
Primary Completion Date: January 2015
Outcome Measures: Small bowel bacterial overgrowth (SBBO)|Unified Parkinson's Disease Rating Scale (UPDRS)|Gastrointestinal Symptom Severity Index (GISSI)|Hospital Anxiety Depression Scale (HAD)|Weight change|PD-specific quality of life questionnaire (PDQ-39)|Paffenbarger physical activity questionnaire (PAQ)
URL: http://ClinicalTrials.gov/show/NCT01662791
| Study 4: Weight Changes in Parkinsonian Patients, Treated With Deep Brain Stimulation
Recruitment: Completed
Study Results: No Results Available
Conditions: Parkinson Disease
Interventions: Procedure: Deep brain stimulation
Sponsor/Collaborators: University Hospital, Bordeaux
Gender: Both
Age Groups: Adult|Senior
Phases:
Enrollment: 20
Funded Bys: Other
Study Types: Interventional
Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Prevention|Masking: Open Label
Other IDs: 9212-02
First Received: September 13, 2005
Start Date: December 2002
Completion Date: December 2006
Last Updated: September 17, 2008
Last Verified: September 2008
Acronym: null
Results First Received: No Study Results Posted
Primary Completion Date: December 2006
Outcome Measures: Measurement of energy expenditure with indirect calorimetry in open chamber: at rest in the morning, without 24h-dopaminergic treatment, and after dopaminergic treatment intake; and post prandial thermogenesis after a test meal.|Weight gain|increase of energy intake|leptin, glucose, insulin blood levels|cognitive and psychological assessments|UDPRS scale
URL: http://ClinicalTrials.gov/show/NCT00221793
Study 5: Impact of Deep Brain Stimulation of Subthalamic Nucleus on the Hepatic Glucose Production in Parkinson's Disease
Recruitment: Terminated
Study Results: No Results Available
Conditions: Idiopathic Parkinson's Disease
Interventions: Behavioral: e.g., Protein and calorie controlled diet; Self-hypnotic relaxation
Sponsor/Collaborators: University Hospital, Clermont-Ferrand
Gender: Both
Age Groups: Adult|Senior
Phases:
Enrollment: 8
Funded Bys: Other
Study Types: Interventional
Study Designs: Allocation: Non-Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Crossover Assignment|Primary Purpose: Diagnostic|Masking: Open Label
Other IDs: CHU-0031
First Received: April 14, 2008
Start Date: April 2008
Completion Date: June 2008
Last Updated: October 7, 2008
Last Verified: October 2008
Acronym: null
Results First Received: No Study Results Posted
Primary Completion Date: June 2008
Outcome Measures: The primary outcome is the hepatic glucose production determined using the 2H2 glucose enrichment measurement and the infusion flow.|-Insulin plasma concentration kinetic -Glucose plasma concentration kinetic -Glucagon plasma concentration kinetic
URL: http://ClinicalTrials.gov/show/NCT00663312
Study 6: Vascular Abnormalities in Idiopathic Parkinson's Disease
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Idiopathic Parkinson's Disease
Interventions:
Sponsor/Collaborators: University of Saskatchewan
Gender: Both
Age Groups: Child|Adult|Senior
Phases:
Enrollment: 30
Funded Bys: Other
Study Types: Observational
Study Designs: Observational Model: Case Control|Time Perspective: Retrospective
Other IDs: BIO13-204
First Received: December 11, 2013
Start Date: December 2013
Completion Date: October 2014
Last Updated: January 22, 2014
Last Verified: December 2013
Acronym: IPD
Results First Received: No Study Results Posted
Primary Completion Date: October 2014
Outcome Measures: Measurement of Vascular Flow within the Internal Jugular Veins(IJVs), External Jugular Veins(EJVs) and Dural Sinus|Measurement of Brian Iron using MRI Susceptibility Weighted Imaging Iron Quantification tools
URL: http://ClinicalTrials.gov/show/NCT02045420
|