Altern Ther Health Med. 2015 Jan-Feb;21(1):8-14. Feldenkrais method-based exercise improves quality of life in individuals with Parkinson's disease: a controlled, randomized clinical trial. Teixeira-Machado L, Araújo FM, Cunha FA, Menezes M, Menezes T, Melo DeSantana J.
CONTEXT: Longevity results in changes to patterns of health, with an increased prevalence of chronic diseases. Parkinson's disease (PD) is described as a progressive neurodegenerative disease related to age that influences quality of life (QoL) and leads to depression.
OBJECTIVE: The study intended to assess changes in QoL and depression in older adults with PD through use of Feldenkrais method-based exercise.
DESIGN: The study was a controlled, blinded, and randomized clinical trial.
SETTING: The study occurred at the University Hospital of the Federal University of Sergipe in Aracaju, Sergipe, Brazil.
PARTICIPANTS: Participants were 30 patients, aged between 50 and 70 y, with idiopathic PD, who signed an informed consent form and were randomly assigned to 2 groups: treatment and control.
INTERVENTION: The treatment group underwent 50 sessions of an exercise program based on the Feldenkrais method. The control group received educational lectures during this period. The treatment group's 50 sessions, given 2 ×/wk on alternate days and lasting 60 min, were conducted in an appropriate room at the hospital.
OUTCOME MEASURES: Two surveys, the Parkinson's Disease Quality of Life (PDQL) questionnaire and the Beck Depression Inventory (BDI), were administered before and after the sessions for both groups. RESULTS: After the exercises based on the Feldenkrais method, the treated group showed improvement in QoL scores (P = .004) as well as a reduction in the level of depression (P = .05) compared with the control group.
CONCLUSION: The findings in the current study indicate that it is likely that the practice of a program based on the Feldenkrais method can contribute greatly to the QoL of patients with PD, suggesting the importance of interventions that promote wellness for this population.
JAMA Neurol. 2013 Feb;70(2):183-90. Randomized clinical trial of 3 types of physical exercise for patients with Parkinson disease. Shulman LM(1), Katzel LI, Ivey FM, Sorkin JD, Favors K, Anderson KE, Smith BA, Reich SG, Weiner WJ, Macko RF. Author information: (1)Univ Maryland School of Medicine, Dept Neurology, Baltimore, MD21201, USA. lshulman@som.umaryland.edu. Comment in JAMA Neurol. 2013 Feb;70(2):156-7.
OBJECTIVE: To compare the efficacy of treadmill exercises and stretching and resistance exercises in improving gait speed, strength, and fitness for patients with Parkinson disease.
DESIGN: A comparative, prospective, randomized, single-blinded clinical trial of 3 types of physical exercise.
SETTING: The Parkinson's Disease and Movement Disorders Center at the University of Maryland and the Baltimore Veterans Affairs Medical Center, Geriatric Research Education and Clinical Center.
PATIENTS: 67 patients with Parkinson's disease who had gait impairment were randomly assigned to 1 of 3 arms of the trial.
INTERVENTIONS; (1) A higher-intensity treadmill exercise (30 minutes at 70%-80% of heart rate reserve), (2) a lower-intensity treadmill exercise (50 minutes at 40%-50% of heart rate reserve), and (3) stretching and resistance exercises (2 sets of 10 repetitions on each leg on 3 resistance machines [leg press, leg extension, and curl]). These exercises were performed 3 times a week for 3 months.
MAIN OUTCOME MEASURES: The primary outcome measures were gait speed (6-minute walk), cardiovascular fitness (peak oxygen consumption per unit time [$$ VO2], and muscle strength (1-repetition maximum strength).
RESULTS: All 3 types of physical exercise improved distance on the 6-minute walk: lower-intensity treadmill exercise (12% increase; P=.001), stretching and resistance exercises (9% increase; P<.02), and higher-intensity treadmill exercise (6% increase; P=.07), with no between-group differences. Both treadmill exercises improved peak $$ VO2 (7%-8% increase; P<.05) more than did the stretching and resistance exercises. Only stretching and resistance improved muscle strength (16% increase; P<.001).
CONCLUSIONS: The effects of exercise were seen across all 3 exercise groups. The lower-intensity treadmill exercise resulted in the greatest improvement in gait speed. Both the higher- and lower-intensity treadmill exercises improved cardiovascular fitness. Only the stretching and resistance exercises improved muscle strength. Therefore, exercise can improve gait speed, muscle strength, and fitness for patients with Parkinson disease. The combination of treadmill and resistance exercises may result in greater benefit and requires further investigation.
Arch Phys Med Rehabil. 2014 May;95(5):996-9. Impact of physical exercise on reaction time in patients with Parkinson's disease-data from the Berlin BIG Study. Ebersbach G(1), Ebersbach A(2), Gandor F(2), Wegner B(3), Wissel J(4), Kupsch A(5). Author information: (1)Movement Disorders Hospital, Beelitz-Heilstätten, Germany, ebersbach@parkinson-beelitz.de. (2)Movement Disorders Hospital, Beelitz-Heilstätten, Germany. (3)Inst Med Biometrics Clin Epidemiology, Charité Univ Medicine Berlin, Berlin, Germany. (4)Vivantes-Klinikum Spandau, Berlin, Germany. (5)Dept Neurol Stereotactic Neurosurgery, Otto-von-Guericke-Univ, Magdeburg, Germany.
OBJECTIVE: To determine whether physical activity may affect cognitive performance in patients with Parkinson's disease by measuring reaction times in patients participating in the Berlin BIG study.
PARTICIPANTS: Patients with mild to moderate Parkinson's disease (N=60) were randomly allocated to 3 treatment arms. Outcome was measured at the termination of training and at follow-up 16 weeks after baseline in 58 patients (completers).
INTERVENTIONS: Patients received 16h of individual Lee Silverman Voice Treatment-BIG training (BIG; duration of treatment, 4wk), 16h of group training with Nordic Walking (WALK; duration of treatment, 8wk), or nonsupervised domestic exercise (HOME; duration of instruction, 1hr).
MAIN OUTCOME MEASURES: Cued reaction time (cRT) and noncued reaction time (nRT).
RESULTS: Differences between treatment groups in improvement in reaction times from baseline to intermediate and baseline to follow-up assessments were observed for cRT but not for nRT. Pairwise t test comparisons revealed differences in change in cRT at both measurements between BIG and HOME groups (intermediate: -52ms; 95% confidence interval [CI], -84/-20; P=.002; follow-up: 55ms; CI, -105/-6; P=.030) and between WALK and HOME groups (intermediate: -61ms; CI, -120/-2; P=.042; follow-up: -78ms; CI, -136/-20; P=.010). There was no difference between BIG and WALK groups (intermediate: 9ms; CI, -49/67; P=.742; follow-up: 23ms; CI, -27/72; P=.361).
CONCLUSION: Supervised physical exercise with Lee Silverman Voice Treatment-BIG or Nordic Walking is associated with improvement in cognitive aspects of movement preparation.
BMC Neurol. 2015 Apr 24;15(1):63. The cyclical lower extremity exercise for Parkinson's trial (CYCLE): methodology for a randomized controlled trial. Rosenfeldt AB(1), Rasanow M(2), Penko AL(3,)(4), Beall EB(5), Alberts JL(6,)(7,)(8). Author information: (1)Dept Biomed Eng, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. rosenfa2@ccf.org. (2)Dept Biomed Eng, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. rasanowm@gmail.com. (3)Dept Biomed Eng, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA. penkoa@ccf.org. (4)Cleveland FES Center, L Stokes Cleveland VA Medical Center, 10701 East Blvd, Cleveland, OH, 44106, USA. penkoa@ccf.org. (5)Imaging Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. bealle@ccf.org. (6)Dept Biomed Eng, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. albertj@ccf.org. (7)Cleveland FES Center, L Stokes Cleveland VA Med Ctr, 10701 East Blvd, Cleveland, OH, 44106, USA. albertj@ccf.org. (8)Ctr Neurolog Restoration, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. albertj@ccf.org.
BACKGROUND: Motor and non-motor impairments affect quality of life in individuals with Parkinson's disease. Our preliminary research indicates that forced exercise cycling, a mode of exercise in which a participant's voluntary rate of exercise is augmented on a stationary cycle, results in global improvements in the cardinal symptoms of Parkinson's disease. The objective of the Cyclical Lower Extremity Exercise (CYCLE) trial for Parkinson's disease is to determine the effects of forced exercise cycling on motor and non-motor performance when compared to voluntary rate cycling and a non-exercise control group. Additionally, we plan to identify any associated changes in neural activity determined by functional magnetic resonance imaging.
METHODS/DESIGN: 100 individuals with mild to moderate idiopathic Parkinson's disease will participate in a single-center, parallel-group, rater-blind study. Participants will be randomized 2:2:1 into a forced exercise, voluntary exercise, or no-exercise control group, respectively. Both exercise groups will cycle 3 times per week for 8 weeks at identical aerobic intensities for 40 minutes, but participants in the forced exercise group will cycle 30% faster than their voluntary rate by means of an augmented motorized bicycle. Neuroimaging, clinical, and biomechanical assessments of motor and non-motor performance will be made at baseline both 'on' and 'off' medication, after 4 weeks of exercise (midpoint), end of treatment, 4 weeks after end of treatment, and 8 weeks after end of treatment.
DISCUSSION: CYCLE trial will play a critical role in determining the effectiveness of 2 different types of aerobic exercise, forced and voluntary, on motor and non-motor performance in individuals with Parkinson's disease. Additionally, the coupling of clinical, biomechanical, and neuroimaging outcomes has the potential to provide insight into mechanisms underlying change in function as a result of exercise.
TRIAL REGISTRATION: Clinicaltrials.gov registration number NCT01636297 .
BMC Neurol. 2015 Apr 16;15(1):56. Design of the Park-in-Shape study: a phase II double blind randomized controlled trial evaluating the effects of exercise on motor and non-motor symptoms in Parkinson's disease. van der Kolk NM(1), Overeem S(2), de Vries NM(3), Kessels RP(4), Donders R(5), Brouwer M(6), Berg D(7), Post B(8), Bloem BR(9). Author information: (1)Dept Neurology, Donders Inst Brain, Cognition, Behavior, Radboud Univ Med Ctr Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Nicolien.vanderKolk@radboudumc.nl. (2)Dept Neurology, Donders Inst Brain, Cognition, Behavior, Radboud Univ Med Ctr Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Sebastiaan.Overeem@radboudumc.nl. (3)Dept Neurology, Donders Inst Brain, Cognition, Behavior, Radboud Univ Med Ctr Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Nienke.deVries-Farrouh@radboudumc.nl. (4)Dept Medical Psychology, Donders Inst Brain, Cognition, Behaviour, Radboud Univ Med Ctr, Nijmegen, the Netherlands. Roy.Kessels@radboudumc.nl. (5)Dept Health Evidence, Radboud Univ Med Ctr Nijmegen, Nijmegen, The Netherlands. Rogier.Donders@radboudumc.nl. (6)Dept Cardiology, Radboudumc, Nijmegen, the Netherlands. Marc.Brouwer@radboudumc.nl. (7)Dept Neurodegeneration, Ctr Neurology and Hertie-Institute Clinical Brain Research, Tübingen, Germany. Daniele.Berg@uni-tuebingen.de. (8)Dept Neurology, Donders Inst Brain, Cognition, Behavior, Radboud Univ Med Ctr Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Bart.Post@radboudumc.nl. (9)Dept Neurology, Donders Inst Brain, Cognition, Behavior, Radboud Univ Med Ctr Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Bas.Bloem@radboudumc.nl.
BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder with a wide range of motor and non-motor symptoms. Despite optimal medical management, PD still results in a high disability rate and secondary complications and many patients lead a sedentary lifestyle, which in turn is also associated with a higher co-morbidity and mortality. Exercise has been explored as a strategy to reduce secondary complications and results suggests that it not only provides general health benefits, but may also provide symptomatic relief. If this holds true exercise would be a very attractive addition to the therapeutic arsenal in PD. The supportive evidence remains incomplete. Here, we describe the design of the Park-in-Shape study, which primarily aims to evaluate whether aerobic exercise affords clinically relevant improvements in motor symptoms in sedentary PD patients. A specific new element is the introduction of gaming to optimize compliance to the exercise intervention.
METHODS/DESIGN: The Park-in-Shape study is a randomized controlled, assessor- and patient-blinded single center study. Parallel groups will include 130 patients, receiving either aerobic exercise on a home trainer equipped with gaming elements ("exergaming"), or a non-aerobic intervention (stretching, flexibility and relaxation exercises). Both groups are supported by a specifically designed motivational app that uses gaming elements to stimulate patients to exercise and rewards them after having completed the exercise. Both interventions are delivered at home at least 3 times a week for 30-45 minutes during 6 months. Eligible patients are community-dwelling, sedentary patients diagnosed with mild-moderate PD. The primary outcome is the MDS-UPDRS motor score (tested in the off state) after 6 months. Secondary outcomes include various motor and non-motor symptoms, quality of life, physical fitness, and adherence.
DISCUSSION: This Park-in-Shape study is anticipated to answer the question whether high intensity aerobic exercise combined with gaming elements ("exergaming") provides symptomatic relief in PD. Strong elements include the double-blinded randomized controlled trial design, the MDS-UPDRS as valid primary outcome, the large sample size and unique combination of home-based pure aerobic exercise combined with gaming elements and motivational aspects.
TRIAL REGISTRATION: Dutch trial register NTR4743.
J Neurol Sci. 2015 Jun 15;353(1-2):9-19. Parkinson's disease and intensive exercise therapy - a systematic review and meta-analysis of randomized controlled trials. Uhrbrand A(1), Stenager E(2), Pedersen MS(3), Dalgas U(3). Author information: (1)Section of Sport Science, Dep. Public Health, Aarhus Univ, Denmark. (2)Inst Regional Health Res, Univ Southern Denmark, Odense, Denmark; Dept Neurology & MS-Clinic of Southern Jutland (Sønderborg, Esbjerg, Vejle), Sønderborg Hospital, Denmark. (3)Section Sport Science, Dep. Public Health, Aarhus Univ, Denmark.
OBJECTIVE: To evaluate and compare the effect of 3 intensive exercise therapy modalities - Resistance Training (RT), Endurance Training (ET) and Other Intensive Training Modalities (OITM) - in Parkinson's Disease (PD). Design A systematic review and meta-analysis of randomized controlled trials.
METHODS: A systematic literature search was conducted (Embase, Pubmed, Cinahl, SPORTDiscus, Cochrane, PEDro), which identified 15 studies that were categorized as RT, ET or OITM. The different exercise modalities were reviewed and a meta-analysis evaluating the effect of RT on muscle strength was made.
RESULTS: In PD intensive exercise therapy (RT, ET and OITM) is feasible and safe. There is strong evidence that RT can improve muscle strength in PD, which is underlined by the meta-analysis (g'=0.54 [95%CI 0.22;0.86]). There is moderate evidence that ET can improve cardio-respiratory fitness in PD. RT, ET and OITM may have beneficial effects on balance, walking performance, Unified Parkinson's Disease Rating Scale-III (UPDRS-III) score and quality of life in PD, but findings are inconsistent. No studies find deterioration in any outcomes following exercise therapy.
CONCLUSION: RT, ET and OITM all represent feasible, safe and beneficial adjunct rehabilitation therapies in PD.
Clinical trials investigating exercise as a treatment for patients with Parkinson's Disease
Study 1: Exercise Targeting Cognitive Impairment in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Skill-Based Exercise|Other: Aerobic Exercise|Other: Social Contact Sponsor/Collaborators: Univ Southern California|National Parkinson Foundation|University of California, Los Angeles Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 150 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: HS-14-00422 First Received: October 14, 2014 Start Date: October 2014 Completion Date: October 2016 Last Updated: May 28, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: October 2016 Outcome Measures: Evaluation of Change in Executive Functioning|Change in Context Dependent Motor Learning (CDML)|Change in Dual Task Performance and Functional Magnetic Resonance Imaging (fMRI)|Change in Parkinson Disease Questionnaire-39 (PDQ-39)|Change in Evaluation of PD Motor Symptoms with Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS)|Change in Activity Specific Balance Confidence (ABC) Scale|Change in Confidence in ability to maintain an exercise program (CONF)|Change in Exercise Control Beliefs (BEL)|Change in Self-efficacy for Exercise Scale (EFFIC)|Change in Frontal Systems Behavior Scale (FrSBe)|Change in Motor Skill Fitness|Change in Cardiovascular Fitness URL: http: //ClinicalTrials.gov/show/NCT02267785
Study 2: Parkinson's Disease Exercise TMS PET Study Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: Exercise|Other: Exercise Sponsor/Collaborators: Pacific Parkinson's Research Centre Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Other IDs: H14-02200 First Received: October 11, 2014 Start Date: November 2014 Completion Date: November 2018 Last Updated: May 8, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: November 2018 Outcome Measures: Change in Dopamine release measured by RAC PET URL: http: //ClinicalTrials.gov/show/NCT02265900
Study 3: The Effects of Exercise in Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease 10 Interventions: Other: Active Exercise|Other: Passive Exercise Sponsor/Collaborators: Pacific Parkinson's Research Centre Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 18 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Basic Science|Masking: Single Blind (Investigator) Other IDs: H13-00276 First Received: April 16, 2013 Start Date: April 2013 Completion Date: March 2015 Last Updated: May 8, 2015 Last Verified: May 2015 Acronym: PET Results First Received: No Study Results Posted Primary Completion Date: March 2015 Outcome Measures: PET|fMRI URL: http: //ClinicalTrials.gov/show/NCT01835652
Study 4: Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease Recruitment: Not yet recruiting Study Results: No Results Available Conditions: Parkinson Disease|Dysphagia Interventions: Other: Swallowing exercise|Other: Breathing Exercises|Other: Swallowing and breathing exercises Sponsor/Collaborators: Federal University of Bahia Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 100 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 96/10 First Received: August 18, 2011 Start Date: April 2014 Completion Date: December 2015 Last Updated: October 20, 2013 Last Verified: October 2013 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: September 2014 Outcome Measures: Swallowing dynamics|Vocal and speech measures|Breathing measures URL: http: //ClinicalTrials.gov/show/NCT01420796
Study 5: Study in Parkinson's Disease of Exercise Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Moderate Exercise|Behavioral: Vigorous Exercise Sponsor/Collaborators: University of Colorado, Denver|University of Illinois at Chicago|University of Pittsburgh|Rush University Medical Center|National Institute of Neurological Disorders and Stroke (NINDS)|Northwestern University Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 126 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 11-1237|R01NS074343 First Received: December 16, 2011 Start Date: April 2012 Completion Date: August 2015 Last Updated: December 16, 2014 Last Verified: December 2014 Acronym: SPARX Results First Received: No Study Results Posted Primary Completion Date: June 2015 Outcome Measures: Adherence to exercise|Potential for therapeutic efficacy URL: http: //ClinicalTrials.gov/show/NCT01506479
Study 6: High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: High intensity exercise and balance training|Other: Usual care arm exercise Sponsor/Collaborators: Univ Nevada, Las Vegas Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Other IDs: CTR-IN UNLVPT 2014.01 First Received: August 27, 2014 Start Date: August 2014 Completion Date: June 2015 Last Updated: May 26, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2015 Outcome Measures: Frequency feasibility|Aerobic feasibility|Strength feasibility|Compliance|Safety|Motivation|Falls|Motor activity|Fatigue|Strength|Cognition|Quality of life|Long term behavioral change|mini-Balance Evaluation Systems Test (mini-BESTest)|Falls self-efficacy|Fall Efficacy|Fall catastrophization|Physical activity|Motor symptoms|Fear of falling|Endurance|bone health|Mood|Catalase|Cytokines URL: http: //ClinicalTrials.gov/show/NCT02230267
Study 7: Sensory Attention Focused Exercise in Parkinson's Disease Recruitment: Active, not recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Sensory Attention Focused Exercise (SAFEx)|Other: Sensory Attention Focused Exercise (SAFEx) Sponsor/Collaborators: Sun Life Financial Movement Disorders Research and Rehabilitation Centre|Canada, Young Men's Christian Association (YMCA)|Parkinson Society Canada|Canada, Sun Life Financial|Canadian Institutes of Health Research (CIHR) Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 76 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Crossover Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 225510 First Received: November 22, 2010 Start Date: June 2008 Completion Date: December 2010 Last Updated: November 22, 2010 Last Verified: September 2010 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2009 Outcome Measures: Unified Parkinson's Disease Rating Scale (UPDRS) III (motor score)|Timed up and go|30 second chair stand|Unified Parkinson's Disease Rating Scale (UPDRS) - I and II (self report of mentation, depression, and activities of daily living).|Grooved Pegboard|Step Length|Velocity|Step to Step Length Variability URL: http: //ClinicalTrials.gov/show/NCT01246700
Study 8: The Cyclical Lower-extremity Exercise for Parkinson's Trial Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Forced exercise|Behavioral: Voluntary exercise|Behavioral: No-exercise/control Sponsor/Collaborators: The Cleveland Clinic Gender: Both Age Groups: Adult|Senior Phases: Phase 2|Phase 3 Enrollment: 100 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Single Group Assignment|Primary Purpose: Supportive Care|Masking: Single Blind (Outcomes Assessor) Other IDs: 1R01NS073717-01 First Received: July 6, 2012 Start Date: June 2013 Completion Date: null Last Updated: August 1, 2013 Last Verified: August 2013 Acronym: CYCLE Results First Received: No Study Results Posted Primary Completion Date: June 2016 Outcome Measures: UPDRS|Trail Making Test|Cortical and Subcortical activation in motor and non-motor regions URL: http: //ClinicalTrials.gov/show/NCT01636297
Study 9: Exercise Interventions in Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Exercise Programme|Behavioral: Hand Writing programme Sponsor/Collaborators: Oxford Brookes University|National Institute for Health Research, United Kingdom|Royal Berkshire NHS Foundation Trust (participant identification centre)|Nuffield Orthopaedic Centre NHS Trust (participant identification centre) Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 105 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: MSG_EXPD_11/SC/0267 First Received: September 15, 2011 Start Date: September 2011 Completion Date: September 2014 Last Updated: October 20, 2014 Last Verified: October 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: September 2014 Outcome Measures: Change in Two minute walk from baseline at 3 months|Change in Two minute walk from 3 months at 6 months|Change in Two minute walk from 6 months at 12 months|Change in Time Up and Go (TUG) from baseline at 3 months|Change in Nine hole peg test from baseline at 3 months|Change in SF-36 from baseline at 3 months|Change in EQ-5D from baseline at 3 months|Change in Prescribed medication from baseline at 3 months|Change in Blood Pressure from baseline at 3 months|Change in Body Mass Index from baseline at 3 months|Change in aerobic fitness from baseline at 3 months|Change in Leg power from baseline at 3 months|Change in Grip Strength from baseline at 3 months|Change in Disease Status from baseline at 3 months|Change in Non-motor symptoms from baseline at 3 months|change in reported Physical Activity from baseline at 3 months|Change measured physical activity from baseline at 3 months|Process Evaluation|Adherence|Change in Time Up and Go (TUG) from 3 months at 6 months|Change in Time Up and Go (TUG) from 6 months at 12 months|Change in Nine hole peg test from 3 months at 6 months|Change in Nine hole peg test from 6 months at 12 months|Change in SF-36 from 6 months at 12 months|Change in SF-36 from 3 months at 6 months|Change in EQ-5D from 3 months at 6 months|Change in EQ-5D from 6 months at 12 months|Change in Prescribed medication from 3 months at 6 months|Change in Prescribed medication from 6 months at 12 months|Change in Blood Pressure from 3 months at 6 months|Change in Blood Pressure from 6 months at 12 months|Change in Body Mass Index from 6 months at 12 months|Change in aerobic fitness from 6 months at 12 months|Change in Leg power from 3 months at 6 months|Change in Leg power from 6 months at 12 months|Change in Grip Strength from 3 months at 6 months|Change in Grip Strength from 6 months at 12 months|Change in Disease Status from 3 months at 6 months|Change in Disease Status from 6 months at 12 months|Change in Non-motor symptoms from 3 months at 6 months|Change in Non-motor symptoms from 6 months at 12 months|Change in reported Physical Activity from 3 months at 6 months|Change in reported Physical Activity from 6 months at 12 months|Change measured physical activity from 3 months at 6 months|Change measured physical activity from 6 months at 12 months|Change in FSS from baseline at 3 months|Change in FSS from 3 months at 6 months|Change in FSS from 6 months at 12 months|Change upper limb function from baseline at 3 months|Change upper limb function from 3 months at 6 months|Change upper limb function from 6 months at 12 months URL: http: //ClinicalTrials.gov/show/NCT01439022
Study 10: COPE-Co-morbidities, Parkinson's Disease and Exercise Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Physical therapy|Behavioral: Group Exercise Class|Behavioral: Home Program Sponsor/Collaborators: Oregon Health and Science University|American Physical Therapy Association Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 58 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 4022 First Received: May 17, 2011 Start Date: March 2011 Completion Date: August 2012 Last Updated: October 1, 2014 Last Verified: August 2012 Acronym: COPE Results First Received: No Study Results Posted Primary Completion Date: August 2012 Outcome Measures: Physical Performance Test|UPDRS ADL and Motor UPDRS ADL and Motor|Timed up and Go Test with and without DT|Gait analysis|MiniBESTest|PDQ-39|LARS apathy scale|Activities of Balance confidence|Self-efficacy for exercise scale URL: http: //ClinicalTrials.gov/show/NCT01361724
Study 11: Non-contact Boxing Training and Traditional Therapeutic Exercise for Persons With Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Traditional Therapeutic Exercise|Behavioral: Non-Contact Boxing Training Sponsor/Collaborators: University of Indianapolis Gender: Both Age Groups: Adult|Senior Phases: Phase 1|Phase 2 Enrollment: 31 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: EXB-01 First Received: November 13, 2009 Start Date: September 2009 Completion Date: March 2011 Last Updated: November 20, 2014 Last Verified: November 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2010 Outcome Measures: Mobility: Measured with the Timed Up and Go Test; Four-Square Step Test; Six-Minute Walk Test; Berg Balance Scale; Functional Reach Test|Participation: measured with the Activities Specific Balance Confidence Scale and the Parkinson's disease Quality of Life Scale URL: http: //ClinicalTrials.gov/show/NCT01014663
Study 12: Effects of Exercise on Long-Range Autocorrelations in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Physical Exercise Sponsor/Collaborators: Cliniques universitaires Saint-Luc- Université Catholique de Louvain Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 50 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Crossover Assignment|Masking: Single Blind (Outcomes Assessor) Other IDs: IONS - Warlop - 01 First Received: April 14, 2015 Start Date: June 2014 Completion Date: null Last Updated: April 16, 2015 Last Verified: April 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2016 Outcome Measures: Balance Evaluation Systems Test (BESTest)|Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS)|Six Minute Walk Distance (6-MWD)|10 Meter Walk Test (10-MWT)|Long-range autocorrelations|Instrumented gait analysis|Impact on Participation and Autonomy Questionnaire (IPAQ)|Activities-specific Balance Confidence Scale (ABC-Scale) URL: http: //ClinicalTrials.gov/show/NCT02419768
Study 13: Virtual Exercises in Patients With Parkinson's Disease. Recruitment: Recruiting Study Results: No Results Available Conditions: Patients With Parkinson's Disease. Interventions: Other: Virtual exercises Sponsor/Collaborators: Faculdade Evangelica do Parana Gender: Both Age Groups: Adult|Senior Phases: Phase 4 Enrollment: 20 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: FEPAR - 04 First Received: December 23, 2013 Start Date: February 2013 Completion Date: February 2014 Last Updated: December 27, 2013 Last Verified: December 2013 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2013 Outcome Measures: Functional exercise capacity|Fatigue URL: http: //ClinicalTrials.gov/show/NCT02023034
Study 14: The Effects of the Hopeful Outdoor Parkinson Exercise (HOPE) Program on Improving Balance Performance in Parkinsonian Non-fallers and Single Fallers Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: an 8-week blended indoor-outdoor exercise program|Behavioral: an 8-week upper limb and hand exercise program Sponsor/Collaborators: The Hong Kong Polytechnic University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 84 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Investigator) Other IDs: approvalletter_20110823001 First Received: February 21, 2013 Start Date: August 2011 Completion Date: December 2014 Last Updated: March 18, 2015 Last Verified: March 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: January 2014 Outcome Measures: Changes from baseline Balance Systems Evaluation Test total and subsection scores at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline comfortable gait speed at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline dual task timed-up-and-go time at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline timed-up-and-go time at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline five-times-sit-to-stand time at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline one-leg stance time at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline Activities-specific Balance Confidence Scale at post 4-week training, post 8-week training, 6- and 12-month follow-ups|Changes from baseline Parkinson's disease Questionnaire (PDQ-39) at post 4-week training, post 8-week training, 6- and 12-month follow-ups URL: http: //ClinicalTrials.gov/show/NCT01799681
Study 15: Exercise for People With Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Aerobic Exercise|Behavioral: Flexibility and Function exercise program|Behavioral: Home exercise program Sponsor/Collaborators: University of Colorado, Denver|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 163 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Investigator) Other IDs: 02-0750|R01HD043770 First Received: December 7, 2010 Start Date: April 2003 Completion Date: July 2010 Last Updated: October 1, 2012 Last Verified: October 2012 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: April 2010 Outcome Measures: Functional Reach URL: http: //ClinicalTrials.gov/show/NCT01257945
Study 16: Effects of Aerobic Exercise in Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: aerobic exercise in the form of brisk walking Sponsor/Collaborators: Department of Veterans Affairs|University of Iowa Gender: Both Age Groups: Adult|Senior Phases: Phase 1|Phase 2 Enrollment: 60 Funded Bys: U.S. Fed|Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: B6261-R First Received: October 30, 2008 Start Date: February 2009 Completion Date: May 2012 Last Updated: November 4, 2014 Last Verified: November 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2012 Outcome Measures: Change in cognition, motor function, quality of life, brain function/structure and biomarkers in response to expected change in fitness|cardiac fitness in response to exercise intervention|safety and tolerability of the intervention URL: http: //ClinicalTrials.gov/show/NCT00784563
Study 17: A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Balance & Strengthening Exercises Sponsor/Collaborators: Boston University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 32 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Crossover Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: BU-SAR-BAL First Received: November 24, 2014 Start Date: December 2011 Completion Date: June 2013 Last Updated: November 24, 2014 Last Verified: November 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2013 Outcome Measures: Falls Diary|Change in Activities-specific Balance Confidence|Change in Falls Self-Efficacy|Change in Balance Evaluation Systems Test (BESTest)|Change in Six-Minute Walk Test|Change in Freezing of Gait Questionnaire|Change in Unified Parkinson's Disease Rating Scale|Change in Scales for Outcomes in Parkinson Disease|Change in Parkinson's Disease Questionnaire-39|Change in Beck Anxiety Inventory|Changes in Beck Depression Inventory Second Edition|Changes in Penn State Worry Questionnaire|Change in Panic Disorder Severity Scale|Changes in Anxiety Sensitivity Index|Changes in Social Phobia Inventor|Changes in Social Interaction Anxiety Scale URL: http: //ClinicalTrials.gov/show/NCT02302144
Study 18: Exercise Intervention and Dexterity in Parkinson Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Interventions: Other: Exercise program Sponsor/Collaborators: Universidad de Granada Gender: Both Age Groups: Adult Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Non-Randomized|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Single Blind (Investigator) Other IDs: DF0036UG First Received: December 12, 2012 Start Date: December 2012 Completion Date: July 2015 Last Updated: December 9, 2014 Last Verified: December 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: July 2015 Outcome Measures: Manual dexterity|Grip strength|Pressure pain measure|Nervous assessment|Risk of falls. URL: http: //ClinicalTrials.gov/show/NCT01749917
Study 19: Chinese Exercise Modalities in Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Chinese exercise modalities Sponsor/Collaborators: National Center for Complementary and Integrative Health (NCCIH) Gender: Both Age Groups: Adult|Senior Phases: Phase 1|Phase 2 Enrollment: 40 Funded Bys: NIH Study Types: Interventional Study Designs: Allocation: Randomized|Primary Purpose: Treatment Other IDs: R01 AT000612-01 First Received: January 23, 2002 Start Date: null Completion Date: null Last Updated: August 17, 2006 Last Verified: July 2006 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: null Outcome Measures: URL: http: //ClinicalTrials.gov/show/NCT00029809
Study 20: Exercise, Brain Imaging, Cognition, and Gait in Parkinsonism Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease|Parkinson Disease, Secondary Vascular|Frontal Gait Disorders Interventions: Behavioral: Exercise Sponsor/Collaborators: Oregon Health and Science University|National Institute on Aging (NIA) Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 96 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Crossover Assignment|Masking: Single Blind (Outcomes Assessor) Other IDs: 4131|2R01AG006457 First Received: August 18, 2014 Start Date: August 2014 Completion Date: March 2019 Last Updated: December 18, 2014 Last Verified: December 2014 Acronym: EEforPD Results First Received: No Study Results Posted Primary Completion Date: March 2019 Outcome Measures: Change in Mini-BESTest score|Change in UPDRS score|Change in New Freezing of Gait questionnaire (NFOGQ) score|Change in PDQ-39 score|Change in Activities of Balance Confidence (ABC) questionnaire score|Change in instrumented gait and balance measures|Change in locomotor neural network functional connectivity strength|Change in Cognitive measures|Change in Activity level URL: http: //ClinicalTrials.gov/show/NCT02231073
Study 21: The ParkCycle Study: Aerobic Exercise in PD Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Exercise Sponsor/Collaborators: Radboud University|The Cleveland Clinic Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 35 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: NL38116.091.11 First Received: March 19, 2012 Start Date: January 2012 Completion Date: October 2014 Last Updated: November 12, 2014 Last Verified: November 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: October 2014 Outcome Measures: Trails A and B task|UPDRS|Cognitive tests|Kinetics tests|questionaires|maximal exercise test|feasibility parameters|neuroplasticity URL: http: //ClinicalTrials.gov/show/NCT01562496
Study 22: Real-time fMRI Neurofeedback for Treatment of Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Neurofeedback and Physical Exercise|Other: Physical Exercise Sponsor/Collaborators: Cardiff University Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: SPON997-11 First Received: May 30, 2013 Start Date: March 2013 Completion Date: January 2014 Last Updated: March 9, 2015 Last Verified: March 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: January 2014 Outcome Measures: Change from Baseline in the 'Movement Disorder Society - Unified Parkinson's Disease Rating Scale' (MDS-UPDRS)|Change from baseline in the 'Parkinson's Disease Questionnaire 39' (PDQ-39)|Change from baseline in the 'Actigraph'|Change from baseline in the 'GaitRite' URL: http: //ClinicalTrials.gov/show/NCT01867827
Study 23: Motor Performance in Parkinson's Disease After High Intensive Exercise or Deep Brain Stimulation Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: High intensive antigravity locomotor exercise|Procedure: Deep Brain Stimulation Sponsor/Collaborators: University of Copenhagen|Hvidovre University Hospital|Bispebjerg Hospital|Danish Parkinson Association Gender: Male Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Non-Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: H-3-2010-051 First Received: September 29, 2011 Start Date: July 2010 Completion Date: September 2013 Last Updated: September 22, 2013 Last Verified: September 2013 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: September 2013 Outcome Measures: Change in Isometric Tremor Approximate Entropy URL: http: //ClinicalTrials.gov/show/NCT01446549
Study 24: Benefits of Exercise and Education for Individuals With Parkinson's Disease (BEEP) Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Procedure: Exercise, Education Sponsor/Collaborators: University of Saskatchewan|Royal University Hospital Foundation Gender: Both Age Groups: Adult|Senior Phases: Phase 1 Enrollment: 45 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind Other IDs: Bio-REB 05-71 First Received: September 9, 2005 Start Date: September 2005 Completion Date: May 2007 Last Updated: October 4, 2007 Last Verified: September 2006 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: null Outcome Measures: all variables measured at baseline, post intervention, months following, and 9 months following.|Stanford Self-Efficacy for Managing Chronic Disease|The Activities-specific Balance Confidence (ABC) Scale|Timed Up and Go Test(TUG)|Northwestern University Disability Scale: |Schwab & England ADL Scale: ) independence in ADL|Parkinson's Disease Questionnaire - Short Form (PDQ - 8): |Beliefs about Symptom Specific Expectancies: |Social and Physical Activities Questionnaire: URL: http: //ClinicalTrials.gov/show/NCT00167453
Study 25: Vitamin B6, B12, Folic Acid and Exercise in Parkinson's Disease Recruitment: Active, not recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Dietary Supplement: PD vitamin supplementation|Other: PD exercise intervention|Other: PD vitamin + exercise Sponsor/Collaborators: New York Institute of Technology|Stony Brook University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Factorial Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: BHS-545 First Received: November 9, 2010 Start Date: May 2008 Completion Date: November 2010 Last Updated: November 10, 2010 Last Verified: November 2010 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: November 2010 Outcome Measures: Plasma homocysteine|Plasma glutathione (GSH)|Plasma glutathione disulfide (GSSG)|GSH: GSSG ratio|Plasma vitamin B6|Plasma vitamin B12|Plasma folate|Balance|Strength|Kinematic gait analysis URL: http: //ClinicalTrials.gov/show/NCT01238926
Study 26: Frontal Cortex and Gait Freezing in Parkinson's Disease: Rehabilitation Impact Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Exercise Sponsor/Collaborators: Oregon Health and Science University|Department of Veterans Affairs Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 20 Funded Bys: Other|U.S. Fed Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Crossover Assignment|Masking: Single Blind (Outcomes Assessor) Other IDs: 8979 First Received: September 3, 2014 Start Date: September 2014 Completion Date: December 2017 Last Updated: September 9, 2014 Last Verified: September 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2017 Outcome Measures: Change in Freezing of Gait Index|Change in the New Freezing of Gait Questionnaire (NFOGQ) score|Change in PDQ-39 score|Change in Activities of Balance Confidence (ABC) Questionnaire score|Change in instrumented gait and balance measures|Change in mini-BESTest score|Change in UPDRS score|Change in locomotor neural network functional connectivity strength|Change in SCOPA-COG score URL: http: //ClinicalTrials.gov/show/NCT02236286
Study 27: Exercise Study For People With Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Exercise, Physical therapy Sponsor/Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 170 Funded Bys: NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Single Blind Other IDs: R01HD043770|COMIRB #02-750 First Received: October 11, 2006 Start Date: December 2002 Completion Date: April 2009 Last Updated: May 21, 2008 Last Verified: May 2008 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: April 2009 Outcome Measures: Balance (Functional Reach)|Economy of movement (Oxygen consumption)|Functional capacity (Continuous Scale Physical Functional Performance Test (Cs-PFP)|UPDRS Motor subscale|UPDRS ADL subscale|Quality of life (PDQ-39)|Spinal Range of Motion (Functional Axial Rotation, FAR)|VO2 submax URL: http: //ClinicalTrials.gov/show/NCT00387218
Study 28: Study of Tai Chi Exercise and Balance in Persons With Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Tai Chi|Behavioral: Strength training|Behavioral: Low-Impact Exercise Control Sponsor/Collaborators: Oregon Research Institute|National Institute of Neurological Disorders and Stroke (NINDS) Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 195 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Investigator, Outcomes Assessor) Other IDs: R01 NS047130|R01NS047130|NS047130 First Received: February 6, 2008 Start Date: October 2008 Completion Date: August 2011 Last Updated: October 10, 2011 Last Verified: October 2011 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2011 Outcome Measures: Balance|gait, physical performance, Unified Parkinson's Disease Rating Scale, falls, Muscle strength URL: http: //ClinicalTrials.gov/show/NCT00611481
Study 29: Swallowing Training in Parkinson`s Disease Recruitment: Completed Study Results: Has Results Conditions: Parkinson's Disease|Deglutition Disorders|Voice Disorders Interventions: Other: Motor exercises for swallowing, breathing and phonation Sponsor/Collaborators: Federal University of Bahia Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 17 Funded Bys: Other Study Types: Interventional Study Designs: Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 249/2008 First Received: May 25, 2010 Start Date: March 2009 Completion Date: December 2010 Last Updated: October 4, 2011 Last Verified: October 2011 Acronym: null Results First Received: May 5, 2011 Primary Completion Date: October 2010 Outcome Measures: Oropharyngeal Swallowing Score|Quality of Life URL: http: //ClinicalTrials.gov/show/NCT01131494
Study 30: The Effect of Exercise on Individuals With Parkinson's Disease Recruitment: Completed Study Results: Has Results Conditions: Parkinson's Disease Interventions: Behavioral: Progressive resistance training|Behavioral: Modified Fitness Counts Sponsor/Collaborators: University of Illinois at Chicago|National Institute of Neurological Disorders and Stroke (NINDS) Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 51 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: R01NS28127|5R01NS028127-16 First Received: December 26, 2007 Start Date: October 2007 Completion Date: October 2011 Last Updated: February 16, 2015 Last Verified: February 2015 Acronym: null Results First Received: December 23, 2014 Primary Completion Date: July 2011 Outcome Measures: Off Medication UPDRS Part III, Motor Subscale Score|On Medication UPDRS-III|L-dopa equivalent-mg/Day|Elbow Flexion Strength|Ankle Plantar Flexion Strength|Elbow Extension Strength|Ankle Dorsiflexion Strength|Percentage of Agonist EMG Signal Contained in the 0-5, 5-15, 15-30, and 35-50 Hz Frequency Bins During Isometric Contractions|The Integral of the First Agonist Burst|Magnitude of the First 30 ms of the Agonist Burst|Magnitude of the Antagonist Burst|Magnitude of the Agonist Burst|Duration of First Agonist Burst|Number of Agonist Bursts|Co-contraction During Limb Acceleration|Qant|Time to Peak Velocity|Peak Movement Velocity|Relaxation Time|Rise Time|Spatiotemporal Gait Analysis|Distance Walked in 6 Minutes|Modified Physical Performance Test|Time on the Timed up and go Test|Berg Balance Scale Score|Functional Reach|Cognitive Function - Stroop Test|Cognitive Function - Brief Test of Attention|Cognitive Function - Digit Span Forward/Backward|Parkinson 's Disease Quality of Life|Epworth Sleepiness Scale|Beck's Depression Inventory|50 ft Walk Time|50 Foot Walk Speed|5 Time Sit to Stand URL: http: //ClinicalTrials.gov/show/NCT00591344
Study 31: Telemedicine Intervention to Improve Physical Function Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Structured exercise|Behavioral: Lifestyle exercise Sponsor/Collaborators: Department of Veterans Affairs Gender: Both Age Groups: Adult|Senior Phases: Phase 3 Enrollment: 158 Funded Bys: U.S. Fed Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Masking: Single Blind (Outcomes Assessor) Other IDs: IIR 11-342 First Received: July 10, 2012 Start Date: January 2013 Completion Date: April 2017 Last Updated: May 12, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: March 2016 Outcome Measures: Fall rate URL: http: //ClinicalTrials.gov/show/NCT01639469
Study 32: Exercise and Cognitive Training in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: treadmill training|Behavioral: computerized memory training Sponsor/Collaborators: Department of Veterans Affairs|University of Maryland Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 121 Funded Bys: U.S. Fed|Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: E7158-R First Received: March 11, 2010 Start Date: October 2010 Completion Date: August 2016 Last Updated: April 8, 2015 Last Verified: April 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: November 2015 Outcome Measures: Improved dual task ability|Executive Function on a Neuropsychological Test Battery|Improvement in instrumental activities of daily living URL: http: //ClinicalTrials.gov/show/NCT01156714
Study 33: Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Resistance Exercise via Negative Eccentric Work|Behavioral: Standard care exercise training Sponsor/Collaborators: University of Utah|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 41 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Factorial Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: IRB # 11900|1R15HD056478-01 First Received: April 21, 2008 Start Date: August 2007 Completion Date: July 2011 Last Updated: September 20, 2011 Last Verified: September 2011 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: July 2011 Outcome Measures: Hypokinesia as measured by movement kinematics and kinetics|Functional mobility as measured by gait / balance URL: http: //ClinicalTrials.gov/show/NCT00665184
Study 34: Mobile Health Technology to Promote Physical Activity in Persons With Parkinson Disease Recruitment: Active, not recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Mobile Health Technology|Behavioral: Stretching & Strengthening Exercises|Behavioral: Walking with Pedometer Sponsor/Collaborators: Boston University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 65 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: BU-SAR-635 First Received: September 24, 2013 Start Date: October 2013 Completion Date: August 2015 Last Updated: July 15, 2014 Last Verified: July 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: August 2015 Outcome Measures: Change from Baseline in Physical Activity Level|Change from Baseline in BriefBEST Balance Test|Change from Baseline in Six Minute Walk Test|Change from Baseline in Falls Self-Efficacy Scale International|Change from Baseline in Unified Parkinson's Disease Rating Scale|Change from Baseline in Parkinson's Disease Questionnaire-39|Change from Baseline in Self-Efficacy Exercise Scale|Change from Baseline in Functional Gait Assessment|Change from Baseline in Fatigue Severity Scale|Change from Baseline in Geriatric Depression Scale|Change from Baseline Apathy Scale|Change from Baseline in Godin Leisure-Time Exercise Questionnaire URL: http: //ClinicalTrials.gov/show/NCT01955889
Study 35: Behavioral Therapy to Treat Urinary Symptoms in Parkinson Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Urinary Incontinence|Nocturia Interventions: Behavioral: Exercise-based behavioral therapy|Behavioral: Behavioral control Sponsor/Collaborators: Atlanta VA Medical Center Gender: Both Age Groups: Adult|Senior Phases: Phase 3 Enrollment: 60 Funded Bys: U.S. Fed Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: D7892W First Received: January 26, 2012 Start Date: September 2012 Completion Date: December 2016 Last Updated: January 14, 2015 Last Verified: January 2015 Acronym: BETTUR PD Results First Received: No Study Results Posted Primary Completion Date: December 2016 Outcome Measures: Bladder diary|Quality of Life Questionnaire URL: http: //ClinicalTrials.gov/show/NCT01520948
Study 36: Cycling in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Cycling at Forced rate|Other: Cycling at self-selected rate Sponsor/Collaborators: Rehabilitation Institute of Chicago Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 24 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: STU00093757 First Received: June 21, 2014 Start Date: June 2014 Completion Date: July 2016 Last Updated: January 23, 2015 Last Verified: January 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2015 Outcome Measures: 6-minute walk test|Stride length|Step Width|Step variability|10 meter walk test|miniBESTest (Balance Evaluation Systems Test) URL: http: //ClinicalTrials.gov/show/NCT02175082
Study 37: Tango for Treatment of Motor and Non-motor Manifestations in Parkinson's Disease. Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Argentinean Tango classes|Other: Simple pamphlet about the exercise in PD Sponsor/Collaborators: McGill University Health Center Gender: Both Age Groups: Adult|Senior Phases: Phase 0 Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: GEN-11-261 First Received: April 5, 2012 Start Date: April 2012 Completion Date: July 2013 Last Updated: April 26, 2012 Last Verified: April 2012 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: April 2013 Outcome Measures: Severity of PD (Unified Parkinson Disease Rating Scale - UPDRS, 2008 version)|Other motor complications|MiniBESTest|The falls questionnaire from the Canadian Longitudinal Study of Aging|Freezing of Gait Questionnare (FOG_Q)|The Purdue Pegboard|The Montreal Cognitive Assessment|The Beck Depression Inventory (BDI)|Apathy Evaluation Scale (AES)|The Krupp Fatigue Severity Scale|The Parkinson's Disease Questionnaire is a quality of life(PDQ-39)|Adherence to treatment|Clinical global impression of change|Exit questionnaire|Adverse events URL: http: //ClinicalTrials.gov/show/NCT01573260
Study 38: Exercise and Parkinson's: Comparing Interventions and Exploring Neural Mechanisms Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Treadmill|Behavioral: Tango|Behavioral: Stretching Sponsor/Collaborators: Washington University School of Medicine Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 120 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 1R01NS077959-01A1 First Received: January 8, 2013 Start Date: February 2013 Completion Date: June 2016 Last Updated: December 8, 2014 Last Verified: December 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2016 Outcome Measures: Change in Walking Velocity from Baseline to 3 Months|Change in Blood oxygen level dependent signal from baseline to 3 months|Change in Mini Balance Evaluation Systems Test (Mini-BESTest) from baseline to 3 months|Change in PDQ-39 from baseline to 3 months|Change in Movement Disorder Society Unified Parkinson Disease Rating Scale Subscale III from baseline to 3 months|Change in Mini Balance Evaluation Systems Test (Mini-BESTest) from 3 to 6 months|Change in Movement Disorder Society Unified Parkinson Disease Rating Scale Subscale III from 3 months to 6 months|Change in PDQ-39 from 3 months to 6 months|Change in walking velocity from 3 months to 6 months URL: http: //ClinicalTrials.gov/show/NCT01768832
Study 39: The Effect of Exercise Training on Gait and Quality of Life in Parkinson's Disease Recruitment: Terminated Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Walking on treadmill|Other: Walking on treadmill|Other: Control group Sponsor/Collaborators: Laval University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 35 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Outcomes Assessor) Other IDs: TTPD-2011 First Received: September 18, 2012 Start Date: October 2010 Completion Date: March 2012 Last Updated: October 3, 2012 Last Verified: September 2012 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2011 Outcome Measures: Change in Gait speed|Change in Endurance walking|Change in Quality of life|Change in Postural Balance|Change in Spatiotemporal parameters of walking|Change in Cognitive impairment|Change in Fear of falling|Change in Depression and anxiety level|Change in Effects of symptoms and motor impairment URL: http: //ClinicalTrials.gov/show/NCT01701128
Study 40: Study of Axial Mobility Exercises in Parkinson Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Exercise Sponsor/Collaborators: Duke University|Office of Rare Diseases (ORD) Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 80 Funded Bys: Other Study Types: Interventional Study Designs: Primary Purpose: Educational/Counseling/Training Other IDs: 199/11694|DUMC-722955R2 First Received: February 24, 2000 Start Date: May 1995 Completion Date: December 1997 Last Updated: June 23, 2005 Last Verified: April 1998 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: null Outcome Measures: URL: http: //ClinicalTrials.gov/show/NCT00004760
Study 41: Effects of Physical Activity on the Brain in Parkinson's Disease (PD) Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: stationary bike exercise|Behavioral: aerobic Sponsor/Collaborators: Charite University, Berlin, Germany Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 20 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Prevention|Masking: Double Blind (Subject, Investigator, Outcomes Assessor) Other IDs: PA_memory_01 First Received: December 3, 2012 Start Date: December 2010 Completion Date: null Last Updated: September 24, 2014 Last Verified: September 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: September 2014 Outcome Measures: UPDRS motor score|Functional/Structural brain changes|Plasma biomarkers|Cognitive Function based on neuropsychological test-performance URL: http: //ClinicalTrials.gov/show/NCT01741584
Study 42: Blood Lactate Concentrations With and Without Exercise in Parkinson's Disease and Multiple Sclerosis Patients Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease|Multiple Sclerosis Interventions: Device: pro5 AIRdaptive Power Plate, Badhoevedorp, The Netherlands Sponsor/Collaborators: Florida State University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 39 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Non-Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 2014: 12658|HPN First Received: July 2, 2014 Start Date: August 2014 Completion Date: December 2015 Last Updated: March 4, 2015 Last Verified: August 2014 Acronym: PDMSLac Results First Received: No Study Results Posted Primary Completion Date: November 2015 Outcome Measures: Blood Lactate Response|Resting Energy Expenditure URL: http: //ClinicalTrials.gov/show/NCT02184494
Study 43: Telemedicine Intervention to Improve Cognitive Function Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Structured exercise|Behavioral: Health education Sponsor/Collaborators: Department of Veterans Affairs Gender: Both Age Groups: Adult|Senior Phases: Phase 3 Enrollment: 128 Funded Bys: U.S. Fed Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Masking: Single Blind (Outcomes Assessor) Other IDs: N1696-I First Received: September 22, 2014 Start Date: December 2014 Completion Date: September 2018 Last Updated: March 3, 2015 Last Verified: March 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2018 Outcome Measures: Cognitive Section of Alzheimer Disease Assessment Scale (ADAS-Cog) URL: http: //ClinicalTrials.gov/show/NCT02248649
Study 44: Ambulosono Rasagiline Musical Walking Study Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Drug: Azilect|Behavioral: Exercise|Other: Music Sponsor/Collaborators: University of British Columbia|Teva Pharmaceutical Industries Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 60 Funded Bys: Other|Industry Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: H13-02074 First Received: July 28, 2014 Start Date: October 2013 Completion Date: March 2017 Last Updated: March 31, 2015 Last Verified: March 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: March 2017 Outcome Measures: Change from baseline in brain imaging signals (fMRI)|Change from baseline in motor symptoms of PD|Change from baseline in cognition of PD URL: http: //ClinicalTrials.gov/show/NCT02207387
Study 45: Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs Recruitment: Recruiting Study Results: No Results Available Conditions: Mild Cognitive Impairment|Alzheimer Disease|Parkinson Disease|Healthy Volunteers Interventions: Behavioral: 3 months exercise intervention program Sponsor/Collaborators: Slovak Academy of Sciences|University Hospital Bratislava Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 35 Funded Bys: Other Study Types: Interventional Study Designs: Intervention Model: Single Group Assignment|Primary Purpose: Prevention|Masking: Open Label Other IDs: UEE-SAS First Received: September 25, 2014 Start Date: September 2014 Completion Date: June 2016 Last Updated: September 28, 2014 Last Verified: September 2014 Acronym: Brain-Muscle Results First Received: No Study Results Posted Primary Completion Date: December 2015 Outcome Measures: muscle microRNAs and myokines|whole body energy metabolism|cognitive function|motoric function|Muscle functional tests URL: http: //ClinicalTrials.gov/show/NCT02253732
Study 46: Behavioral Therapy to Treat Urinary Incontinence in Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Urinary Incontinence|Parkinson's Disease Interventions: Other: Exercise-based behavioral therapy Sponsor/Collaborators: Atlanta VA Medical Center|The John A. Hartford Foundation Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 28 Funded Bys: U.S. Fed|Other Study Types: Interventional Study Designs: Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 6-38941 First Received: March 19, 2009 Start Date: October 2008 Completion Date: October 2011 Last Updated: January 10, 2012 Last Verified: January 2012 Acronym: BETTUR PD Results First Received: No Study Results Posted Primary Completion Date: October 2011 Outcome Measures: Bladder diary|Quality of Life Questionnaire URL: http: //ClinicalTrials.gov/show/NCT00866710
Study 47: Dance Exercise as Novel Complementary Therapy for Parkinson's Disease Recruitment: Enrolling by invitation Study Results: No Results Available Conditions: We Aim to Study Gait and Balance Issues Associated With Parkinson's Disease Interventions: Sponsor/Collaborators: Beth Israel Deaconess Medical Center|Goldberg Foundation Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Observational Study Designs: Observational Model: Cohort|Time Perspective: Prospective Other IDs: 2010-P-000029 First Received: July 14, 2010 Start Date: July 2010 Completion Date: December 2011 Last Updated: June 23, 2011 Last Verified: June 2011 Acronym: DANCE-PD Results First Received: No Study Results Posted Primary Completion Date: December 2011 Outcome Measures: Balance and Gait improvement URL: http: //ClinicalTrials.gov/show/NCT01163344
Study 48: A Pilot Study of Mirabegron and Behavioral Modification Including Pelvic Floor Exercise for Overactive Bladder in Parkinson's Disease (MAESTRO) Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinsons Disease Interventions: Drug: Mirabegron|Drug: Placebo Sponsor/Collaborators: Daniel Burdick, MD|Astellas Pharma US, Inc.|Burdick, Daniel, M.D. Gender: Both Age Groups: Adult|Senior Phases: Phase 4 Enrollment: 40 Funded Bys: Other|Industry Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Investigator) Other IDs: DBPA-2013-01 First Received: March 7, 2014 Start Date: March 2014 Completion Date: May 2016 Last Updated: January 26, 2015 Last Verified: July 2014 Acronym: Maestro Results First Received: No Study Results Posted Primary Completion Date: March 2016 Outcome Measures: Change in the mean daily Overactive Bladder-Symptom Composite Score.|Secondary Outcome Measures based on clinic visits URL: http: //ClinicalTrials.gov/show/NCT02092181
Study 49: Dual Task Practice in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: physical therapy Sponsor/Collaborators: Katholieke Universiteit Leuven|University Medical Center Nijmegen Gender: Both Age Groups: Adult|Senior Phases: Phase 3 Enrollment: 120 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Masking: Single Blind (Outcomes Assessor) Other IDs: Gossweiler Foundation|Duality-Gossweiler First Received: June 15, 2011 Start Date: June 2011 Completion Date: December 2015 Last Updated: October 10, 2014 Last Verified: October 2014 Acronym: Duality-PD Results First Received: No Study Results Posted Primary Completion Date: December 2014 Outcome Measures: Gait speed during dual task conditions (untrained Auditory Stroop task, trained Digit Span)|Functional Dual task, single task gait measures, cognitive outcomes, Freezing of Gait Questionnaire, Quality of life scores (PDQ39)|Fall rate as determined by weekly phonecall URL: http: //ClinicalTrials.gov/show/NCT01375413
Study 50: Assessing the Role of Exercise Intensity in Slowing Disease Progression in Early Parkinson’s Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Sponsor/Collaborators: Austin Health Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Observational Study Designs: Observational Model: Defined Population|Observational Model: Natural History|Time Perspective: Longitudinal|Time Perspective: Prospective Other IDs: 126/05 First Received: October 5, 2006 Start Date: April 2005 Completion Date: December 2007 Last Updated: October 5, 2006 Last Verified: October 2006 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: null Outcome Measures: URL: http: //ClinicalTrials.gov/show/NCT00385073
Study 51: Robot Walking Rehabilitation in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Idiopathic Parkinson's Disease|Progressive Supranuclear Palsy Interventions: Device: Robot-assisted walking (G-EO-System End Effector lower limb Robot)|Procedure: Inpatient rehabilitation Sponsor/Collaborators: IRCCS San Raffaele Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 80 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Single Blind (Subject) Other IDs: 545/2012/61/2012 First Received: May 8, 2012 Start Date: February 2012 Completion Date: February 2014 Last Updated: August 17, 2012 Last Verified: August 2012 Acronym: Robopark Results First Received: No Study Results Posted Primary Completion Date: August 2013 Outcome Measures: 6 minuts walking test.|Time Up and Go test.|Gait Parameters URL: http: //ClinicalTrials.gov/show/NCT01668407
Study 52: The Effects of Treadmill Versus Agility Training in Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Exercise|Parkinson's Disease Interventions: Behavioral: Aerobic vs. Agility Training Sponsor/Collaborators: Oregon Health and Science Univ Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 4402 First Received: September 22, 2009 Start Date: January 2009 Completion Date: January 2011 Last Updated: October 31, 2014 Last Verified: October 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: January 2011 Outcome Measures: Dynamic Posturography|UPDRS URL: http: //ClinicalTrials.gov/show/NCT00982709
Study 53: Efficacy of a Robotic-assisted Gait Training in Addition to a Conventional Physical Therapy in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Device: Lokomat (Hocoma, Zurich, Switzerland)|Other: Conventional physical treatment Sponsor/Collaborators: Habilita, Ospedale di Sarnico Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Investigator, Outcomes Assessor) Other IDs: RAR06 First Received: June 10, 2014 Start Date: June 2014 Completion Date: July 2014 Last Updated: June 20, 2014 Last Verified: June 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: July 2014 Outcome Measures: Timed 6 meter walking test|Movement Disorder Society-Unified Parkinson's Disease Rating Scale Disease rating scale motor sub-scores)|Functional Independence Measure|Barthel Index|Tinetti Test|Parkinson's Disease Questionnaire -39 item URL: http: //ClinicalTrials.gov/show/NCT02164162
Study 54: Improving Dexterous Skills in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Dexterity training program|Behavioral: Theraband training program Sponsor/Collaborators: Luzerner Kantonsspital Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 60 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: Luzerner Kantonsspital First Received: November 17, 2014 Start Date: February 2014 Completion Date: August 2016 Last Updated: April 2, 2015 Last Verified: April 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2015 Outcome Measures: Nine Hole Peg Test|Coin Rotation task|Modified MDS-UPDRS scale II|PDQ-39|Dexterity Questionnaire URL: http: //ClinicalTrials.gov/show/NCT02297893
Study 55: Masked Faces in Parkinson Disease: Mechanism and Treatment Recruitment: Completed Study Results: Has Results Conditions: Parkinson's Disease Interventions: Behavioral: Respiratory muscle strength training Sponsor/Collaborators: Univ Florida|National Inst Neurological Disorders and Stroke (NINDS) Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 44 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Investigator) Other IDs: R01NS050633 First Received: July 5, 2006 Start Date: December 2004 Completion Date: November 2009 Last Updated: April 4, 2012 Last Verified: April 2012 Acronym: null Results First Received: February 6, 2012 Primary Completion Date: November 2009 Outcome Measures: Change in Facial Entropy Score From Baseline [Off Dopamine Medication]|Change in Facial Entropy Score From Baseline [On Dopamine Medication]|Change in Parkinson Disease Quality of Life-39 Scale (PDQ-39) URL: http: //ClinicalTrials.gov/show/NCT00350402
Study 56: Functional Improvement in Patients With Parkinson's Disease After Training in Real or Virtual Environment Recruitment: Completed Study Results: No Results Available Conditions: Parkinson´s Disease Interventions: Device: Balance Training with Nintendo Wii Fit|Other: Physical Therapy Sponsor/Collaborators: Sao Camilo University Center Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 32 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Non-Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: saocamilo-sp First Received: April 16, 2012 Start Date: August 2009 Completion Date: April 2012 Last Updated: April 18, 2012 Last Verified: April 2012 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: August 2011 Outcome Measures: UNIFIED PARKINSON'S DISEASE RATING SCALE|Berg Balance Scale URL: http: //ClinicalTrials.gov/show/NCT01580787
Study 57: Effectiveness of Physiotherapy Interventions for Patients With Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: Physiotherapy Interventions|Other: Education Classes Sponsor/Collaborators: Queen Elizabeth Hospital, Hong Kong Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 112 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: KCKESOP0016a First Received: February 25, 2010 Start Date: March 2010 Completion Date: October 2012 Last Updated: March 9, 2010 Last Verified: March 2010 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: October 2012 Outcome Measures: Movement Disorder Society-Unified Parkinson's Disease Rating Scale|Levodopa equivalent daily dosage (LEDD)|Timed Up and Go Test|Activities-Specific Balance Confidence Scale (Chinese version)|Parkinson's Disease Questionnaire (Standard Chinese Version)|Number of Injurious Falls URL: http: //ClinicalTrials.gov/show/NCT01076712
Study 58: Consolidation of Motor Learning of Writing Skills and Its Related Brain Activity Changes in Parkinson&Apos;s Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Writing program|Behavioral: Stretch & Relaxation program Sponsor/Collaborators: Katholieke Universiteit Leuven|Research Foundation Flanders Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Supportive Care|Masking: Open Label Other IDs: G.0906.11 First Received: November 3, 2014 Start Date: January 2013 Completion Date: July 2016 Last Updated: November 7, 2014 Last Verified: November 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: July 2016 Outcome Measures: Change from baseline in writing amplitude (cm) on tablet after 6 weeks of training|Change from baseline in writing amplitude (cm) on tablet after 12 weeks, including 6 weeks without training|Change from baseline in brain activity during writing (functional MRI) after 6 weeks of training|Change from baseline in brain activity during rest (resting state MRI) after 6 weeks of training|Change from baseline in Diffusion Tensor Imaging after 6 weeks of training|Transfer of change in writing amplitude to an untrained writing sequence after 6 weeks of training|Transfer of change in writing amplitude to an untrained writing sequence after 12 weeks, including 6 weeks without training|Change from baseline in dual task effect (DTE) for writing amplitude after 6 weeks of training|Change from baseline in dual task effect (DTE) for writing amplitude after 12 weeks, including 6 weeks without training|Change from baseline in writing fluency (normalized jerk) on tablet after 6 weeks of training|Change from baseline in writing fluency (normalized jerk) on tablet after 12 weeks, including 6 weeks without training|Systematic Screening of handwriting difficulties (writing on paper) - change from baseline in quality score after 6 weeks of training|Systematic Screening of handwriting difficulties (writing on paper) - change from baseline in quality score after 12 weeks, including 6 weeks without training|Systematic Screening of handwriting difficulties (writing on paper) - change from baseline in writing speed after 6 weeks of training|Systematic Screening of handwriting difficulties (writing on paper) - change from baseline in writing speed after 12 weeks, including 6 weeks without training|Change from baseline in Purdue Pegboard test after 6 weeks of training|Change from baseline in Purdue Pegboard test after 12 weeks, including 6 weeks without training URL: http: //ClinicalTrials.gov/show/NCT02288052
Study 59: A Randomized Controlled Feasibility Trial to Determine the Effectiveness of Set Dancing for People With Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Intervention group Sponsor/Collaborators: University of Limerick Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 24 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Investigator, Outcomes Assessor) Other IDs: ST1 First Received: December 1, 2012 Start Date: December 2012 Completion Date: August 2013 Last Updated: August 25, 2013 Last Verified: August 2013 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: August 2013 Outcome Measures: Berg Balance Scale (To assess change in balance)|Unified Parkinson's Disease Rating Scale 3 (UPDRS-3) (To assess changes in motor impairment)|The Parkinson's Disease Questionnaire (PDQ-39) (To assess change in health related quality of life)|Six-Minute Walk Test (To assess change of functional exercise tolerance)|Zarit Care Giver Burden Interview (ZCBI)(To assess changes in caregiver burden) URL: http: //ClinicalTrials.gov/show/NCT01757509
Study 60: Stability and Balance in Locomotion Through Exercise Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: treadmill walking|Device: Treadmill Sponsor/Collaborators: Univ Erlangen-Nürnberg|Deutsche Stiftung Neurologie (DSN)|Department of Molecular Neurology, Faculty of Medicine, Univ Erlangen-Nürnberg Gender: Both Age Groups: Adult|Senior Phases: Phase 1 Enrollment: 60 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: DSN-0613 First Received: May 8, 2013 Start Date: June 2013 Completion Date: null Last Updated: July 2, 2014 Last Verified: July 2014 Acronym: StaBLE Results First Received: No Study Results Posted Primary Completion Date: May 2015 Outcome Measures: Change from Baseline Gait Speed|Change from Baseline Balance|Change from Baseline Gait Performance|Change from Baseline Mobility|Change from Baseline Unified Parkinson's Disease Rating Scale (UPDRS) URL: http: //ClinicalTrials.gov/show/NCT01856244
Study 61: Balance Training in Parkinson's Disease Using the Wii Balance Board Recruitment: Completed Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Balance Training Sponsor/Collaborators: Rehabilitation Institute of Chicago Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 10 Funded Bys: Other Study Types: Interventional Study Designs: Endpoint Classification: Safety/Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 30775 First Received: August 31, 2010 Start Date: August 2010 Completion Date: February 2011 Last Updated: July 26, 2011 Last Verified: July 2011 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: November 2010 Outcome Measures: Berg Balance Scale|Dynamic Gait Index|Parkinson's Disease QOL Questionnaire (PDQ-8)|Postural Sway URL: http: //ClinicalTrials.gov/show/NCT01228851
Study 62: PD4PD: Partnered Dance for Parkinson Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Tango dancing Sponsor/Collaborators: Washington Univ School of Medicine|Parkinson's Disease Foundation Gender: Both Age Groups: Adult|Senior Phases: Phase 2|Phase 3 Enrollment: 62 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: PD4PD-09-0168|PDF First Received: June 29, 2011 Start Date: July 2009 Completion Date: June 2011 Last Updated: July 5, 2011 Last Verified: July 2011 Acronym: PD4PD Results First Received: No Study Results Posted Primary Completion Date: June 2011 Outcome Measures: Motor Symptom Severity URL: http: //ClinicalTrials.gov/show/NCT01388556
Study 63: The Effect of High-Volume Walking With Visual Cues (VC) in Parkinson´s Disease (PD) Recruitment: Completed Study Results: No Results Available Conditions: Parkinson´s Disease Interventions: Other: Visual Cues|Other: Walking without visual cues Sponsor/Collaborators: University of Iceland|The Icelandic Parkinson´s Association.|Icelandic Physiotherapy Association Gender: Both Age Groups: Child|Adult|Senior Phases: Phase 3 Enrollment: 26 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: 123SmOkE First Received: July 7, 2011 Start Date: April 2008 Completion Date: September 2008 Last Updated: July 11, 2011 Last Verified: March 2010 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: September 2008 Outcome Measures: Change in Step Length|Change in Gait Velocity|Change in Stride Time Variability|Change in Timed Up & Go (seconds) URL: http: //ClinicalTrials.gov/show/NCT01391741
Study 64: Walking Capacity in Parkinson's Disease (PD-Walk) Recruitment: Terminated Study Results: No Results Available Conditions: Idiopathic Parkinson's Disease Interventions: Behavioral: Treadmill training Sponsor/Collaborators: Natalie Allen|South West Sydney Local Health District|University of Sydney Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 20 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: U3189 First Received: December 1, 2005 Start Date: May 2005 Completion Date: September 2012 Last Updated: May 27, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: December 2006 Outcome Measures: Distance walked in 6 minutes|Unified Parkinson's disease Rating Scale (UPDRS) - motor examination|The Parkinson's disease Questionnaire (PDQ-39|Walking Automaticity, determined as the velocity of walking 10m while performing a concurrent (cognitive or cognitive + physical) task expressed as a percentage of the velocity of walking 10m without performing the concurrent task.|Walking consistency determined as the co-efficients of variation for stride time and stride length recorded during the 6 minute walk test. URL: http: //ClinicalTrials.gov/show/NCT00261781
Study 65: Structured Physical Activity for Sleep Quality and Daytime Sleepiness in Patients With Parkinson's Disease Recruitment: Terminated Study Results: No Results Available Conditions: Parkinson's Disease|Poor Quality Sleep|Hypersomnia Interventions: Behavioral: Structured Physical Activity|Behavioral: Sleep hygiene education Sponsor/Collaborators: Northwestern University|Rehabilitation Institute of Chicago Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 1 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: STU00045490|67-PA-11 First Received: February 22, 2012 Start Date: August 2011 Completion Date: March 2014 Last Updated: March 20, 2014 Last Verified: March 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: March 2014 Outcome Measures: Change in polysomnographically-derived wake after sleep onset|Change in mean sleep latency test-derived mean sleep latency|Change in Pittsburgh Sleep Quality Index|Change in Epworth Sleepiness Scale URL: http://ClinicalTrials.gov/show/NCT01544465
Study 66: Working on Asymmetry in Parkinson's Disease Recruitment: Not yet recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Behavioral: Physical Therapy WSI|Behavioral: Physical Therapy BSI|Behavioral: Physical Therapy ST Sponsor/Collaborators: Neuromed IRCCS Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 42 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Supportive Care|Masking: Double Blind (Investigator, Outcomes Assessor) Other IDs: ASPD-01 First Received: January 16, 2014 Start Date: March 2014 Completion Date: September 2014 Last Updated: February 14, 2014 Last Verified: February 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2014 Outcome Measures: Motor Symptoms|Freezing of gait URL: http://ClinicalTrials.gov/show/NCT02051556
Study 67: Walking While Talking: The Effect of Doing Two Things at Once in Individuals With Neurological Injury or Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease|Huntington's Disease|Multiple Sclerosis|Traumatic Brain Injury Interventions: Behavioral: Gait-cognitive training|Behavioral: Identification of at risk variables Sponsor/Collaborators: Stony Brook University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 100 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Non-Randomized|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 64249 First Received: July 30, 2013 Start Date: April 2013 Completion Date: null Last Updated: November 17, 2014 Last Verified: November 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: April 2015 Outcome Measures: Spatiotemporal measures of gait across conditions and over time.|Changes in cognitive performance measured with serial sevens. URL: http://ClinicalTrials.gov/show/NCT01917903
Study 68: Computer-based Cognitive Training for Individuals With Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease|Mild Cognitive Impairment Interventions: Behavioral: Brain Fitness|Behavioral: InSight|Behavioral: Active Control Sponsor/Collaborators: Virginia Commonwealth University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: ADWilliams2012-647173 First Received: August 19, 2014 Start Date: April 2012 Completion Date: June 2015 Last Updated: August 22, 2014 Last Verified: August 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2015 Outcome Measures: Percent Accuracy on Cognitive Training Quizzes|Parkinson's Disease Quality of Life Questionnaire-39 (PDQ-39)|California Verbal Learning Test-II Long Delay Free Recall Scaled Score Change Over 3 Months URL: http://ClinicalTrials.gov/show/NCT02225314
Study 69: Virtual Reality in Motor Performance and Quality of Life in Patients With Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: treatment with Nintendo wii.|Other: Physical therapy conventional. Sponsor/Collaborators: Federal University of Bahia Gender: Both Age Groups: Adult|Senior Phases: Phase 2|Phase 3 Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: DNEP First Received: May 10, 2010 Start Date: May 2011 Completion Date: October 2011 Last Updated: December 6, 2011 Last Verified: December 2011 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: September 2011 Outcome Measures: Quality of life|Motor performance URL: http://ClinicalTrials.gov/show/NCT01120392
Study 70: Gait Training With Executive Functions Tasks in Subjects With Parkinson´s Disease: A Randomised Controlled Trial Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson´s Disease Interventions: Behavioral: Gait training executive functions tasks|Behavioral: Gait training alone Sponsor/Collaborators: Univ Sao Paulo|Coordination for the Improvement of Higher Education Personnel Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: USPNEC002 First Received: July 19, 2012 Start Date: July 2012 Completion Date: July 2013 Last Updated: November 6, 2012 Last Verified: November 2012 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2013 Outcome Measures: Dynamic Gait Index|Montreal Cognitive Assessment URL: http://ClinicalTrials.gov/show/NCT01650623
Study 71: Efficacy of Voice Treatment for Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease|Dysphagia|Dysarthria Interventions: Behavioral: Voice/Respiration Treatment|Behavioral: Speech/Articulation Treatment|Behavioral: No intervention (PD)|Behavioral: HC control Sponsor/Collaborators: Univ Colorado, Boulder|National Institute on Deafness and Other Communication Disorders (NIDCD) Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 620 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Subject) Other IDs: R01 DC01150|R01DC001150 First Received: July 20, 2005 Start Date: March 2002 Completion Date: December 2012 Last Updated: May 6, 2011 Last Verified: May 2011 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2011 Outcome Measures: Voice intensity; voice fundamental frequency; articulatory acoustics; physiological voice function; speech intelligibility; swallowing function; non-verbal communication behaviors; limb function; neural imaging; neuropsychological functioning URL: http://ClinicalTrials.gov/show/NCT00123084
Study 72: BETA Study: Improving Balance Function in Elderly by Progressive and Specific Training and Physical Activity Recruitment: Active, not recruiting Study Results: No Results Available Conditions: Elderly|Parkinsons Disease|Osteoporosis Interventions: Other: Gait and balance group training|Other: Nordic walking (only osteoporosis group) Sponsor/Collaborators: Karolinska Institutet|The Swedish Research Council Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 200 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: K2011-69P-20908-02-4 First Received: August 15, 2011 Start Date: January 2010 Completion Date: June 2016 Last Updated: March 31, 2015 Last Verified: March 2015 Acronym: BETA Results First Received: No Study Results Posted Primary Completion Date: June 2015 Outcome Measures: Improved balance control|Improved gait|Improved physical activity|Reduced Fear of falling|Improved health related quality of life URL: http://ClinicalTrials.gov/show/NCT01417598
Study 73: Central and Peripheral Fatigue in Individuals With Parkinson's Disease - Evaluation and Training Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease(PD) Interventions: Device: Electronic muscle stimulator|Other: Muscle strength training Sponsor/Collaborators: Chang Gung University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 90 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 100-3167A3 First Received: October 18, 2013 Start Date: February 2012 Completion Date: null Last Updated: April 23, 2014 Last Verified: April 2014 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: January 2015 Outcome Measures: Muscle twitch force|Muscle voluntary activity level|Muscle strength test for lower extremities.|The central activation and the excitability of motor cortex URL: http://ClinicalTrials.gov/show/NCT01971528
Study 74: Guided Self-Help for Depression in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Depression|Parkinson's Disease Interventions: Behavioral: Guided Cognitive-Behavioral Self-Help Sponsor/Collaborators: University of Medicine and Dentistry of New Jersey|Rutgers, The State University of New Jersey Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 2013002798 First Received: May 29, 2013 Start Date: April 2013 Completion Date: April 2015 Last Updated: January 26, 2015 Last Verified: January 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: April 2015 Outcome Measures: The Hamilton Depression Rating Scale|Beck Depression Inventory|Hamilton Anxiety Rating Scale|Inference Questionnaire|Caregiver Distress Scale|Insomnia Severity Index|Medical Outcomes Short Form|Feasibility and adherence measures|Clinical Global Impression-Improvement Scale URL: http://ClinicalTrials.gov/show/NCT01935050
Study 75: Hallux Mobilization in Patients With Parkinson's Disease Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: MIRT|Other: Mobilization of the metatarsophalangeal joint of the hallux Sponsor/Collaborators: Ospedale Generale Di Zona Moriggia-Pelascini Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 100 Funded Bys: Other Study Types: Observational Study Designs: Observational Model: Case Control|Time Perspective: Cross-Sectional Other IDs: HalluxPD001|Hallux PD 001 First Received: March 21, 2014 Start Date: March 2013 Completion Date: February 2014 Last Updated: March 24, 2014 Last Verified: March 2014 Acronym: HalluxPD001 Results First Received: No Study Results Posted Primary Completion Date: November 2013 Outcome Measures: FOGQ|UPDRS III|BBS|Hallux URL: http://ClinicalTrials.gov/show/NCT02098642
Study 76: Tai Chi for Enhancing Motor and Cognitive Function in Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: Tai Chi Sponsor/Collaborators: Harvard University Faculty of Medicine|Spaulding Rehabilitation Hospital|Beth Israel Deaconess Medical Center Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Supportive Care|Masking: Single Blind (Outcomes Assessor) Other IDs: 2013P002343 First Received: April 6, 2015 Start Date: May 2014 Completion Date: May 2016 Last Updated: April 13, 2015 Last Verified: April 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: May 2016 Outcome Measures: Rate of participant recruitment|Protocol adherence|Retention|Change from Baseline in Unified Parkinson's Disease Rating Scale (UPDRS)|Change from Baseline in PDQ-39|Change from Baseline in Physical Activity Status Scale (PASS)|Change from Baseline in Self-Efficacy for Exercise Scale|Change from Baseline in Activity-specific Balance Confidence Scale|Change from Baseline in Profile of Mood State|Change from Baseline in Single leg stance time|Change from Baseline in Timed Up and Go Test|Change from Baseline in Steady state gait dynamics|Change from Baseline in Balance/Postural control|Change from Baseline in Cognitive function URL: http://ClinicalTrials.gov/show/NCT02418780
Study 77: NET-PD LS-1 Creatine in Parkinson's Disease Recruitment: Terminated Study Results: Has Results Conditions: Parkinson's Disease Interventions: Drug: creatine|Other: placebo Sponsor/Collaborators: University of Rochester|National Institute of Neurological Disorders and Stroke (NINDS) Gender: Both Age Groups: Child|Adult|Senior Phases: Phase 3 Enrollment: 1741 Funded Bys: Other|NIH Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Other IDs: U01NS43128 NET-PD|CRC First Received: March 20, 2007 Start Date: March 2007 Completion Date: May 2014 Last Updated: March 23, 2015 Last Verified: March 2015 Acronym: null Results First Received: February 19, 2015 Primary Completion Date: September 2013 Outcome Measures: The Global Outcome Combined Information on Change From Baseline in Schwab England Activities of Daily Living, 39-Item Parkinson's Disease Questionnaire, Ambulatory Capacity, Symbol Digit Modalities, and Modified Rankin at 5 Years. URL: http://ClinicalTrials.gov/show/NCT00449865
Study 78: Randomized Trial to Test the "Coordinated Care for Health Promotion and Activities in Parkinson's Disease" Intervention in the Veterans Administration Recruitment: Enrolling by invitation Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: Coordinated care management for Parkinson's disease|Other: Educational handout Sponsor/Collaborators: Department of Veterans Affairs Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 400 Funded Bys: U.S. Fed Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Health Services Research|Masking: Single Blind (Outcomes Assessor) Other IDs: NRI 11-126 First Received: January 13, 2012 Start Date: July 2012 Completion Date: April 2017 Last Updated: April 7, 2015 Last Verified: April 2015 Acronym: CHAPS Results First Received: No Study Results Posted Primary Completion Date: March 2016 Outcome Measures: Change from Baseline in Adherence to the guidelines for Parkinson's disease care at 18 months|Health Utilities Index (HUI)|General Self-Efficacy Scale (GSES)|WHO-Five Well-being index (WHO-5)|PHQ-9|The Consumer Assessment of Health Plans (CAHPS)|Patient Assessment of Care for Chronic Conditions (PACIC)|Change from Baseline in Health Utilities Index (HUI) at 12 months|Change from Baseline in General Self-Efficacy Scale (GSES) at 12 months|Change from Baseline in WHO-Five Well-being index (WHO-5) at 12 months|Change from Baseline in PHQ-9 at 12 months|Change from Baseline in The Consumer Assessment of Health Plans (CAHPS) at 12 months|Change from Baseline in Patient Assessment of Care for Chronic Conditions (PACIC) at 12 months|Change from Baseline in Health Utilities Index (HUI) at 18 months|Change from Baseline in General Self-Efficacy Scale (GSES) at 18 months|Change from Baseline in WHO-Five Well-being index (WHO-5) at 18 months|Change from Baseline in PHQ-9 at 18 months|Change from Baseline in The Consumer Assessment of Health Plans (CAHPS) at 18 months|Change from Baseline in Patient Assessment of Care for Chronic Conditions (PACIC) at 18 months|Change from Baseline in General Self-Efficacy Scale (GSES) at 24 months|Change from Baseline in WHO-Five Well-being index (WHO-5) at 24 months|Change from Baseline in PHQ-9 at 24 months|Change from Baseline in The Consumer Assessment of Health Plans (CAHPS) at 24 months|Change from Baseline in Patient Assessment of Care for Chronic Conditions (PACIC) at 24 months URL: http://ClinicalTrials.gov/show/NCT01532986
Study 79: Gait Training With Executive Functions Tasks in Subjects With Parkinson´s Disease: A Study Protocol Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson´s Disease Interventions: Behavioral: Gait training executive functions tasks Sponsor/Collaborators: University of Sao Paulo|Coordination for the Improvement of Higher Education Personnel Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Interventional Study Designs: Endpoint Classification: Efficacy Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: USPNEC001 First Received: July 19, 2012 Start Date: July 2012 Completion Date: July 2013 Last Updated: November 6, 2012 Last Verified: November 2012 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: February 2013 Outcome Measures: Dynamic Gait Index|Montreal Cognitive Assessment URL: http://ClinicalTrials.gov/show/NCT01650610
Study 80: MIRT and Rotigotine in the Early Stage of PD Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Multidisciplinary intensive rehabilitation treatment|Drug: Rotigotine Sponsor/Collaborators: Ospedale Generale Di Zona Moriggia-Pelascini Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Observational Study Designs: Observational Model: Cohort|Time Perspective: Prospective Other IDs: MIRT-RT First Received: March 24, 2014 Start Date: January 2013 Completion Date: June 2014 Last Updated: March 26, 2014 Last Verified: March 2014 Acronym: MIRT-RT Results First Received: No Study Results Posted Primary Completion Date: March 2014 Outcome Measures: UPDRS total score|UPDRS II|UPDRS III|6MWT|BBS|TUG|CGS and FGS|SPDDS URL: http://ClinicalTrials.gov/show/NCT02100176
Study 81: Transcranial Direct Current Stimulation for Freezing of Gait Recruitment: Enrolling by invitation Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Device: Transcranial Direct Current Stimulation (tDCS)|Other: locomotor training|Other: sham-tDCS Sponsor/Collaborators: University of Miami Gender: null Age Groups: Child|Adult|Senior Phases: Phase 1|Phase 2 Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Safety/Efficacy Study|Intervention Model: Crossover Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Outcomes Assessor) Other IDs: 20140127 First Received: October 7, 2014 Start Date: October 2014 Completion Date: December 2015 Last Updated: October 10, 2014 Last Verified: October 2014 Acronym: TDCS-FOG Results First Received: No Study Results Posted Primary Completion Date: October 2015 Outcome Measures: walking speed|UPDRS|Stride length|Freezing of gait Questionnaire URL: http://ClinicalTrials.gov/show/NCT02266004
Study 82: Effects Of tDCS With Physical Therapy On Rehabilitation In Parkinson's Disease Recruitment: Completed Study Results: Has Results Conditions: Parkinson Disease Interventions: Device: tDCS|Behavioral: Physiotherapy Sponsor/Collaborators: Universidade Federal de Pernambuco Gender: Both Age Groups: Adult|Senior Phases: Phase 2 Enrollment: 12 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Subject, Investigator) Other IDs: Parkinson_tDCS_rehabilitation First Received: June 11, 2013 Start Date: January 2010 Completion Date: December 2012 Last Updated: May 14, 2015 Last Verified: June 2013 Acronym: null Results First Received: February 26, 2015 Primary Completion Date: September 2012 Outcome Measures: Change From Unified Parkinson´s Disease Rating Scale - UPDRS|Change From Cortical Excitability Via Single Transcranial Magnetic Stimulation URL: http://ClinicalTrials.gov/show/NCT01877148
Study 83: A Randomized Controlled Trial to Determine the Effectiveness of Set Dancing for People With Parkinson's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson's Disease Interventions: Other: Dance group Sponsor/Collaborators: University of Limerick Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 72 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Double Blind (Investigator, Outcomes Assessor) Other IDs: ST2 First Received: August 25, 2013 Start Date: August 2013 Completion Date: June 2015 Last Updated: May 28, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2015 Outcome Measures: MiniBEST Test (To assess change in balance)|The Parkinson's Disease Questionnaire (PDQ-39) (To assess change in quality of life)|Unified Parkinson's Disease Rating Scale 3 (UPDRS-3) (To assess change in motor impairment)|Six-Minute Walk Test (To assess change in functional exercise tolerance)|Exit Questionnaire (To assess participants satisfaction)|Screening Questionnaire (To assess past dance experience) URL: http://ClinicalTrials.gov/show/NCT01939717
Study 84: Resistance Training in Patients With Parkinson`s Disease. Recruitment: Completed Study Results: No Results Available Conditions: Parkinson Disease Interventions: Other: Resistance Training|Other: Lectures on the disease Sponsor/Collaborators: University of Brasilia Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 40 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Non-Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: RT-PD First Received: May 12, 2015 Start Date: January 2013 Completion Date: December 2014 Last Updated: May 13, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: June 2014 Outcome Measures: Bradykinesia measured with Unified Parkinson's Disease Rating Scale, section III|Functional Performance measured with Ten Meters Walk Test.|Muscle strength measured with isokinetic peak torque. URL: http://ClinicalTrials.gov/show/NCT02447146
Study 85: Motor Training in PD Recruitment: Recruiting Study Results: No Results Available Conditions: Parkinson Disease Interventions: Behavioral: Adapted Tango Dancing|Behavioral: Behavioral Control (BC) Condition Sponsor/Collaborators: Department of Veterans Affairs Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 99 Funded Bys: U.S. Fed Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Supportive Care|Masking: Open Label Other IDs: N0870-W First Received: May 21, 2015 Start Date: November 2014 Completion Date: January 2018 Last Updated: May 26, 2015 Last Verified: May 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: July 2017 Outcome Measures: Percent signal change|Connectivity strength URL: http://ClinicalTrials.gov/show/NCT02457832
Study 86: BEWARE: Body Awareness Training in the trEatment of Wearing-off Related Anxiety in Patients With paRkinson's Disease Recruitment: Enrolling by invitation Study Results: No Results Available Conditions: Parkinsonism, Experimental|Parkinsonism, Treatment as Usual Interventions: Behavioral: Body awareness therapy|Other: Physical therapy Sponsor/Collaborators: VU University Medical Center|Parkinsonvereniging Gender: Both Age Groups: Child|Adult|Senior Phases: Enrollment: 36 Funded Bys: Other Study Types: Interventional Study Designs: Allocation: Randomized|Endpoint Classification: Efficacy Study|Intervention Model: Parallel Assignment|Primary Purpose: Treatment|Masking: Single Blind (Outcomes Assessor) Other IDs: CWO/13-05E First Received: January 30, 2014 Start Date: January 2014 Completion Date: December 2014 Last Updated: February 3, 2014 Last Verified: February 2014 Acronym: BEWARE Results First Received: No Study Results Posted Primary Completion Date: December 2014 Outcome Measures: Self-efficacy|Anxiety|Depression|Balance performance|comfortable walking speed|Quality of life|Wearing-off symptoms|Activities of Daily Living independence|Freezing of Gait|Comfortable walking speed|Quality of Life|Freezing of gait URL: http://ClinicalTrials.gov/show/NCT02054845
Study 87: Treadmill Walking in Individuals With Dementia With Lewy Bodies and Huntington's Disease Recruitment: Recruiting Study Results: No Results Available Conditions: Huntington Disease|Lewy Body Disease Interventions: Other: Treadmill Walking Sponsor/Collaborators: Ohio State University Gender: Both Age Groups: Adult|Senior Phases: Enrollment: 30 Funded Bys: Other Study Types: Interventional Study Designs: Endpoint Classification: Safety Study|Intervention Model: Single Group Assignment|Primary Purpose: Treatment|Masking: Open Label Other IDs: 2012H0385 First Received: October 10, 2014 Start Date: February 2013 Completion Date: December 2015 Last Updated: April 20, 2015 Last Verified: April 2015 Acronym: null Results First Received: No Study Results Posted Primary Completion Date: August 2015 Outcome Measures: Vital signs|Spatiotemporal gait measures|Timed Up and Go Test|Q-motor testing URL: http://ClinicalTrials.gov/show/NCT02268617
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